Join us to make healthcare more intelligent. For everyone.

You've spent years sharpening your craft. Use your hard earned skills to work on problems that matter. The software we build here directly impacts lives.

View Open Positions
careers.py
def should_you_apply(you: Engineer):
    """Only one way to find out."""

    reasons = [
        you.wants_real_impact,
        you.loves_building,
        you.high_agency,
        you.learns_constantly,
        you.questions_assumptions,
    ]

    if any(reasons):
        apply()

We are on a mission to remove the fear of the unknown.

Each sample represents a patient receiving insights that could change the course of their healthcare journey. Our products detect the most challenging prenatal genetics non-invasively, uncover over 50% more cancer treatment options, and track tumors months earlier than imaging.

Why Engineering at BillionToOne

Build What Matters

You'll write code for patients waiting on test results and providers making decisions under pressure. A smoother lab workflow or a clearer result screen might seem like small things, but your attention to detail will directly improve patient and provider experiences.

Small Teams, Real Ownership

Our engineering teams stay small because we want everyone working on problems that move the company forward. We hire people we trust, hand them real ownership, and get out of their way.

Battle-Tested Stack, Fast Iteration

Python, React, TypeScript, AWS, Postgres. We choose battle-hardened foundations so we can ship quickly and confidently. We instrument what we build and measure what matters before it reaches a patient.

The People

Engineers who join tend to stay, and when you ask them why, they point to the team. We're building a low-ego team with people who are thoughtful, curious, and easy to collaborate with.

Open Positions

We're looking for engineers who are intrinsically motivated and hold themselves to the highest standards. Every role directly impacts patient outcomes.

“We are at our best when we serve others... Let us be scientists for humanity.”
- Jane Goodall

Our science begins with people. Every act of precision, collaboration, and care advances a shared mission—to bring intelligent, compassionate healthcare to every life we touch.

Our Mission

BillionToOne spaces, designed for breakthrough work

At BillionToOne, innovation happens everywhere — from our state-of-the-art labs to our collaborative creative spaces. We equip every employee, on-site or remote, with cutting-edge tools and technology designed to amplify creativity, precision, and impact.

Menlo Park headquarters
Menlo Park, CA
Headquarters, Lab 2.0 (CLIA + CAP)
Union City lab
Union City, CA
Lab 3.0 (CLIA + CAP)
Austin office
Austin, TX
Coming Soon

Benefits and Perks

Growth & Development

Career Growth & Development

Ongoing learning, mentorship, and structured programs to advance your skills.

Post-Baccalaureate CGMBS Training Program

One-year internal program: 35 hrs/week hands-on, 5 hrs/week didactic; CDPH-approved; ASCP prep.

Open, Transparent Culture

Weekly town halls and clear communication across teams.

Compensation & Ownership

Meaningful Equity-Based Compensation

All positions have some variable pay component, which allows employees to generate an increase in pay based on their performance.

401(k) Retirement Plan

Retirement plan with up to a 4% company match and immediate vesting.

Development & Advancement

Performance reviews twice per year to promote multiple opportunities for development and advancement.

On-Campus & Commuter Perks

Transportation & Commuter Support

CarShare access, and WiFi-enabled commuter shuttles connecting BART, Caltrain, and San Francisco.

Complimentary Fitness Centers

Onsite gyms with classes, weights, pools, saunas, climbing walls and more.

Catered Lunches & Stocked Kitchens

Daily catered lunches from local favorites; fully stocked kitchens.

Work Environment

Generous PTO

Paid time off that increases with tenure.

State-of-the-Art Tools & Spaces

Advanced equipment, hardware, and software in cutting-edge labs and collaborative work areas.

Health & Family

Comprehensive Health Coverage

Multiple medical plans; employee premiums 100% on select plans, dependents covered up to 80%. Dental & vision included.

Fertility & Family Support

Supplemental fertility benefits to support every path to family.

Paid Family & Parental Leave

16 weeks of 100% paid time off for eligible employees.

Ready to Build Something Extraordinary?

View Open Positions